StrBio 2022-23

Author

Modesto Redrejo Rodríguez

Published

September 1, 2022

Modified

August 29, 2023

New Version!

A more recent version of this site for the year 2023 is available here.

About

This site contains the materials for the Structural Bioinformatics course of fall 2022 in the Master’s Degree in Bioinformatics & Computational Biology @UAM. All these materials is open access and it is shared under CC BY-NC license. Detailed academic information about the course contents, dates and assessment only can be found at the UAM Moodle site.

Link to the website of the Master’s Degree in Bioinformatics & Computational Biology at UAM

Besides some already classic books, reviews, and articles that are referenced, the contents of this short course are also largely inspired by the works of others that shared their course materials, tips, and other resources on their own blogs or websites, as well as discussions on Twitter, including Alexandre Bovin, Sergey Ovchinnikov, Martin Steinegger and Carlos Outeiral, among many others. I tried to acknowledge (and link!) each one of those contributions but I’d like to apologize beforehand for those that I may have not mentioned.

The course contains three practical exercises that will guide you through the use of Pymol for molecules visualization and modeling proteins by homology modeling and alphafold. Moreover, in some of the sections there are several exercises/questions, highlighted in green that pretend to motivate you to think about the acquired knowledge and skills and go a little bit forward in the interpretation of the results.

As a suggestion, I would also like to invite you to check the set of exercises on Structural Bioinformatics from the Pontificia Universidad Católica de Chile, described in Engelberger et al. (2021): https://github.com/pb3lab/ibm3202

Under construction

Note that this site is a draft under development and I only expect to have a first complete version by the end of the semester at the earliest (December 2022). Any feedback, help or suggestions will be very warmly welcome.

Contact

Please let me know if you find some mistake or a missing reference. Definitely, I’ll appreciate any suggestion, request or correction. You can reach me by email or Twitter.